"Due to adverse conditions, all flights have been temporarily stopped for air safety," the airport said in a statement.
Officials said flights would be suspended until at least 6:00 pm (1500 GMT).
Turkish media said it marked the first time the airport had completely shut down due to adverse weather since it opened.
Located on the Black Sea coast about 40 kilometres (25 miles) northwest of central Istanbul, the air hub serviced more than 37 million passengers last year, according to the transportation ministry.
Istanbul was hit by its first snow storm of the winter over the weekend.