The Dar es Salaam based side kicked off the season fairly well after forcing Azam FC to a one-all draw before going down 3-0 to titleholders Young Africans.
They shared spoils with JKT Ruvu and finally secured their first win of the season with a 3-1 thrashing of ailing Mbao FC at the Uhuru Stadium.
Toto Africans are placed 13th with three points from four matches. The Mwanza team has won only one match, experiencing of their worst starts to the season.
They will, however, head into the match looking to get their season on track, thus Lyon should get prepared for a more hungry side.